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Early Behavioral Abnormalities and Perinatal Alterations of PTEN/AKT Pathway in Valproic Acid Autism Model Mice

Exposure to valproic acid (VPA) during pregnancy has been linked with increased incidence of autism, and has repeatedly been demonstrated as a useful autism mouse model. We examined the early behavioral and anatomical changes as well as molecular changes in mice prenatally exposed to VPA (VPA mice)....

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Detalles Bibliográficos
Autores principales: Yang, Eun-Jeong, Ahn, Sangzin, Lee, Kihwan, Mahmood, Usman, Kim, Hye-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829151/
https://www.ncbi.nlm.nih.gov/pubmed/27071011
http://dx.doi.org/10.1371/journal.pone.0153298