Cargando…

The Upregulation of Genomic Imprinted DLK1-Dio3 miRNAs in Murine Lupus Is Associated with Global DNA Hypomethylation

Epigenetic factors such as DNA methylation and microRNAs (miRNAs) are now increasingly recognized as vital contributors to lupus etiology. In this study, we investigated the potential interaction of these two epigenetic factors in lupus-prone MRL-lpr mice. We recently reported dysregulated expressio...

Descripción completa

Detalles Bibliográficos
Autores principales: Dai, Rujuan, Lu, Ran, Ahmed, S. Ansar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829153/
https://www.ncbi.nlm.nih.gov/pubmed/27070142
http://dx.doi.org/10.1371/journal.pone.0153509