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Genetic Diversity in the Major Capsid L1 Protein of HPV-16 and HPV-18 in the Netherlands
OBJECTIVES: Intratypic molecular variants of human papillomavirus (HPV) type-16 and -18 exist. In the Netherlands, a bivalent vaccine, composed of recombinant L1 proteins from HPV-16 and -18, is used to prevent cervical cancer since 2009. Long-term vaccination could lead to changes in HPV-16 and -18...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829201/ https://www.ncbi.nlm.nih.gov/pubmed/27070907 http://dx.doi.org/10.1371/journal.pone.0152782 |