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Binding Cooperativity Matters: A GM(1)-Like Ganglioside-Cholera Toxin B Subunit Binding Study Using a Nanocube-Based Lipid Bilayer Array

Protein-glycan recognition is often mediated by multivalent binding. These multivalent bindings can be further complicated by cooperative interactions between glycans and individual glycan binding subunits. Here we have demonstrated a nanocube-based lipid bilayer array capable of quantitatively eluc...

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Detalles Bibliográficos
Autores principales: Worstell, Nolan C., Krishnan, Pratik, Weatherston, Joshua D., Wu, Hung-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829222/
https://www.ncbi.nlm.nih.gov/pubmed/27070150
http://dx.doi.org/10.1371/journal.pone.0153265