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Binding Cooperativity Matters: A GM(1)-Like Ganglioside-Cholera Toxin B Subunit Binding Study Using a Nanocube-Based Lipid Bilayer Array
Protein-glycan recognition is often mediated by multivalent binding. These multivalent bindings can be further complicated by cooperative interactions between glycans and individual glycan binding subunits. Here we have demonstrated a nanocube-based lipid bilayer array capable of quantitatively eluc...
Autores principales: | Worstell, Nolan C., Krishnan, Pratik, Weatherston, Joshua D., Wu, Hung-Jen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829222/ https://www.ncbi.nlm.nih.gov/pubmed/27070150 http://dx.doi.org/10.1371/journal.pone.0153265 |
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