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Suppressor of Cytokine Signaling-2 (SOCS2) Regulates the Microglial Response and Improves Functional Outcome after Traumatic Brain Injury in Mice

Traumatic brain injury (TBI) is frequently characterized by neuronal, axonal and myelin loss, reactive gliosis and neuroinflammation, often associated with functional deficits. Endogenous repair mechanisms include production of new neurons from precursor cells, but usually the new neurons fail to in...

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Detalles Bibliográficos
Autores principales: Basrai, Harleen S., Christie, Kimberly J., Turbic, Alisa, Bye, Nicole, Turnley, Ann M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829250/
https://www.ncbi.nlm.nih.gov/pubmed/27071013
http://dx.doi.org/10.1371/journal.pone.0153418