Non-sequential and multi-step splicing of the dystrophin transcript

The dystrophin protein encoding DMD gene is the longest human gene. The 2.2 Mb long human dystrophin transcript takes 16 hours to be transcribed and is co-transcriptionally spliced. It contains long introns (24 over 10kb long, 5 over 100kb long) and the heterogeneity in intron size makes it an ideal...

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Detalles Bibliográficos
Autores principales: Gazzoli, Isabella, Pulyakhina, Irina, Verwey, Nisha E., Ariyurek, Yavuz, Laros, Jeroen F. J., 't Hoen, Peter A. C., Aartsma-Rus, Annemieke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829307/
https://www.ncbi.nlm.nih.gov/pubmed/26670121
http://dx.doi.org/10.1080/15476286.2015.1125074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829307/
https://www.ncbi.nlm.nih.gov/pubmed/26670121
http://dx.doi.org/10.1080/15476286.2015.1125074

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