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Retention and splicing complex (RES) – the importance of cooperativity

One of the great challenges to structural biologists lies in explaining the complexities of the spliceosome – a ribosome-sized molecular machine that is assembled in a step-wise manner and is responsible for pre-mRNA splicing. The spliceosome is both fascinating and difficult to work with, because o...

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Detalles Bibliográficos
Autores principales: Wysoczanski, Piotr, Zweckstetter, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829318/
https://www.ncbi.nlm.nih.gov/pubmed/26479714
http://dx.doi.org/10.1080/15476286.2015.1096484