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New hypotheses derived from the structure of a flaviviral Xrn1-resistant RNA: Conservation, folding, and host adaptation

Arthropod-borne flaviviruses (FVs) are a growing world-wide health threat whose incidence and range are increasing. The pathogenicity and cytopathicity of these single-stranded RNA viruses are influenced by viral subgenomic non-protein-coding RNAs (sfRNAs) that the viruses produce to high levels dur...

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Detalles Bibliográficos
Autores principales: Kieft, Jeffrey S, Rabe, Jennifer L, Chapman, Erich G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829329/
https://www.ncbi.nlm.nih.gov/pubmed/26399159
http://dx.doi.org/10.1080/15476286.2015.1094599