Maternal LSD1/KDM1A is an essential regulator of chromatin and transcription landscapes during zygotic genome activation

Upon fertilization, the highly specialised sperm and oocyte genomes are remodelled to confer totipotency. The mechanisms of the dramatic reprogramming events that occur have remained unknown, and presumed roles of histone modifying enzymes are just starting to be elucidated. Here, we explore the fun...

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Detalles Bibliográficos
Autores principales: Ancelin, Katia, Syx, Laurène, Borensztein, Maud, Ranisavljevic, Noémie, Vassilev, Ivaylo, Briseño-Roa, Luis, Liu, Tao, Metzger, Eric, Servant, Nicolas, Barillot, Emmanuel, Chen, Chong-Jian, Schüle, Roland, Heard, Edith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Developmental Biology and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829419/
https://www.ncbi.nlm.nih.gov/pubmed/26836306
http://dx.doi.org/10.7554/eLife.08851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829419/
https://www.ncbi.nlm.nih.gov/pubmed/26836306
http://dx.doi.org/10.7554/eLife.08851

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