Maternally provided LSD1/KDM1A enables the maternal-to-zygotic transition and prevents defects that manifest postnatally

Somatic cell nuclear transfer has established that the oocyte contains maternal factors with epigenetic reprogramming capacity. Yet the identity and function of these maternal factors during the gamete to embryo transition remains poorly understood. In C. elegans, LSD1/KDM1A enables this transition...

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Detalles Bibliográficos
Autores principales: Wasson, Jadiel A, Simon, Ashley K, Myrick, Dexter A, Wolf, Gernot, Driscoll, Shawn, Pfaff, Samuel L, Macfarlan, Todd S, Katz, David J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Developmental Biology and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829428/
https://www.ncbi.nlm.nih.gov/pubmed/26814574
http://dx.doi.org/10.7554/eLife.08848

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829428/
https://www.ncbi.nlm.nih.gov/pubmed/26814574
http://dx.doi.org/10.7554/eLife.08848

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