Astrocytes contribute to synapse elimination via type 2 inositol 1,4,5-trisphosphate receptor-dependent release of ATP

Selective elimination of unwanted synapses is vital for the precise formation of neuronal circuits during development, but the underlying mechanisms remain unclear. Using inositol 1,4,5-trisphosphate receptor type 2 knockout (Itpr2(−/−)) mice to specifically disturb somatic Ca(2+) signaling in astro...

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Detalles Bibliográficos
Autores principales: Yang, Junhua, Yang, Hongbin, Liu, Yali, Li, Xia, Qin, Liming, Lou, Huifang, Duan, Shumin, Wang, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829431/
https://www.ncbi.nlm.nih.gov/pubmed/27067238
http://dx.doi.org/10.7554/eLife.15043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829431/
https://www.ncbi.nlm.nih.gov/pubmed/27067238
http://dx.doi.org/10.7554/eLife.15043

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