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Enhancing Transgene Expression from Recombinant AAV8 Vectors in Different Tissues Using Woodchuck Hepatitis Virus Post-Transcriptional Regulatory Element

Adeno-associated virus (AAV) vectors have been utilized extensively in gene therapy and gene function studies, as strong transgene expression is a prerequisite for positive outcomes. AAV8 was reported as the most efficient AAV serotype for transduction of the liver, brain and muscle compared with ot...

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Detalles Bibliográficos
Autores principales: Wang, Lizheng, Wang, Zixuan, Zhang, Fangfang, Zhu, Rui, Bi, Jinpeng, Wu, Jiaxin, Zhang, Haihong, Wu, Hui, Kong, Wei, Yu, Bin, Yu, Xianghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829541/
https://www.ncbi.nlm.nih.gov/pubmed/27076785
http://dx.doi.org/10.7150/ijms.14152