Paths of Heritable Mitochondrial DNA Mutation and Heteroplasmy in Reference and gas-1 Strains of Caenorhabditis elegans

Heteroplasmy—the presence of more than one mitochondrial DNA (mtDNA) sequence type in a cell, tissue, or individual—impacts human mitochondrial disease and numerous aging-related syndromes. Understanding the trans-generational dynamics of mtDNA is critical to understanding the underlying mechanisms...

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Detalles Bibliográficos
Autores principales: Wernick, Riana I., Estes, Suzanne, Howe, Dana K., Denver, Dee R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829587/
https://www.ncbi.nlm.nih.gov/pubmed/27148352
http://dx.doi.org/10.3389/fgene.2016.00051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829587/
https://www.ncbi.nlm.nih.gov/pubmed/27148352
http://dx.doi.org/10.3389/fgene.2016.00051

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