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Paths of Heritable Mitochondrial DNA Mutation and Heteroplasmy in Reference and gas-1 Strains of Caenorhabditis elegans

Heteroplasmy—the presence of more than one mitochondrial DNA (mtDNA) sequence type in a cell, tissue, or individual—impacts human mitochondrial disease and numerous aging-related syndromes. Understanding the trans-generational dynamics of mtDNA is critical to understanding the underlying mechanisms...

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Detalles Bibliográficos
Autores principales:	Wernick, Riana I., Estes, Suzanne, Howe, Dana K., Denver, Dee R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829587/ https://www.ncbi.nlm.nih.gov/pubmed/27148352 http://dx.doi.org/10.3389/fgene.2016.00051

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