Cargando…

3D replicon distributions arise from stochastic initiation and domino-like DNA replication progression

DNA replication dynamics in cells from higher eukaryotes follows very complex but highly efficient mechanisms. However, the principles behind initiation of potential replication origins and emergence of typical patterns of nuclear replication sites remain unclear. Here, we propose a comprehensive mo...

Descripción completa

Detalles Bibliográficos
Autores principales: Löb, D., Lengert, N., Chagin, V. O., Reinhart, M., Casas-Delucchi, C. S., Cardoso, M. C., Drossel, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829661/
https://www.ncbi.nlm.nih.gov/pubmed/27052359
http://dx.doi.org/10.1038/ncomms11207