Real-time imaging of glutamate clearance reveals normal striatal uptake in Huntington disease mouse models

It has become well accepted that Huntington disease (HD) is associated with impaired glutamate uptake, resulting in a prolonged time-course of extracellular glutamate that contributes to excitotoxicity. However, the data supporting this view come largely from work in synaptosomes, which may overrepr...

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Detalles Bibliográficos
Autores principales: Parsons, Matthew P., Vanni, Matthieu P., Woodard, Cameron L., Kang, Rujun, Murphy, Timothy H., Raymond, Lynn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829692/
https://www.ncbi.nlm.nih.gov/pubmed/27052848
http://dx.doi.org/10.1038/ncomms11251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829692/
https://www.ncbi.nlm.nih.gov/pubmed/27052848
http://dx.doi.org/10.1038/ncomms11251

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