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Real-time imaging of glutamate clearance reveals normal striatal uptake in Huntington disease mouse models
It has become well accepted that Huntington disease (HD) is associated with impaired glutamate uptake, resulting in a prolonged time-course of extracellular glutamate that contributes to excitotoxicity. However, the data supporting this view come largely from work in synaptosomes, which may overrepr...
Autores principales: | Parsons, Matthew P., Vanni, Matthieu P., Woodard, Cameron L., Kang, Rujun, Murphy, Timothy H., Raymond, Lynn A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829692/ https://www.ncbi.nlm.nih.gov/pubmed/27052848 http://dx.doi.org/10.1038/ncomms11251 |
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