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Abundance of megalin and Dab2 is reduced in syncytiotrophoblast during placental malaria, which may contribute to low birth weight

Placental malaria caused by Plasmodium falciparum contributes to ~200,000 child deaths annually, mainly due to low birth weight (LBW). Parasitized erythrocyte sequestration and consequent inflammation in the placenta are common attributes of placental malaria. The precise molecular details of placen...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Lybbert, Jared, Gullingsrud, Justin, Chesnokov, Olga, Turyakira, Eleanor, Dhorda, Mehul, Guerin, Philippe J., Piola, Patrice, Muehlenbachs, Atis, Oleinikov, Andrew V.
Format: Online Artikel Text
Sprache:English
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829923/
https://www.ncbi.nlm.nih.gov/pubmed/27072056
http://dx.doi.org/10.1038/srep24508