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Critical Length of PEG Grafts on lPEI/DNA Nanoparticles for Efficient in Vivo Delivery

[Image: see text] Nanoparticle-mediated gene delivery is a promising alternative to viral methods; however, its use in vivo, particularly following systemic injection, has suffered from poor delivery efficiency. Although PEGylation of nanoparticles has been successfully demonstrated as a strategy to...

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Detalles Bibliográficos
Autores principales: Williford, John-Michael, Archang, Maani M., Minn, Il, Ren, Yong, Wo, Mark, Vandermark, John, Fisher, Paul B., Pomper, Martin G., Mao, Hai-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829937/
https://www.ncbi.nlm.nih.gov/pubmed/27088129
http://dx.doi.org/10.1021/acsbiomaterials.5b00551