DNA variants in CACNA1C modify Parkinson disease risk only when vitamin D level is deficient

OBJECTIVE: To evaluate the association between the genetic variants in CACNA1C, which encodes the α1 subunit of the L-type voltage-sensitive calcium channel (LVSCC) and Parkinson disease (PD) while accounting for interactions with vitamin D concentration. METHODS: Two independent case-control data s...

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Detalles Bibliográficos
Autores principales: Wang, Liyong, Maldonado, Lizmarie, Beecham, Gary W., Martin, Eden R., Evatt, Marian L., Ritchie, James C., Haines, Jonathan L., Zabetian, Cyrus P., Payami, Haydeh, Pericak-Vance, Margaret A., Vance, Jeffery M., Scott, William K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830205/
https://www.ncbi.nlm.nih.gov/pubmed/27123490
http://dx.doi.org/10.1212/NXG.0000000000000072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830205/
https://www.ncbi.nlm.nih.gov/pubmed/27123490
http://dx.doi.org/10.1212/NXG.0000000000000072

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