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YAP Is a Critical Inducer of SOCS3, Preventing Reactive Astrogliosis

Yes-associated protein (YAP) is a key transcriptional cofactor of the Hippo pathway, critical for the development of multiple organs. However, its role in the developing brain remains poorly understood. Here, we found that YAP was highly expressed in astrocytes and YAP deletion elevated the astrocyt...

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Detalles Bibliográficos
Autores principales: Huang, Zhihui, Wang, Ying, Hu, Guoqing, Zhou, Jiliang, Mei, Lin, Xiong, Wen-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830299/
https://www.ncbi.nlm.nih.gov/pubmed/26679195
http://dx.doi.org/10.1093/cercor/bhv292