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YAP Is a Critical Inducer of SOCS3, Preventing Reactive Astrogliosis
Yes-associated protein (YAP) is a key transcriptional cofactor of the Hippo pathway, critical for the development of multiple organs. However, its role in the developing brain remains poorly understood. Here, we found that YAP was highly expressed in astrocytes and YAP deletion elevated the astrocyt...
Autores principales: | Huang, Zhihui, Wang, Ying, Hu, Guoqing, Zhou, Jiliang, Mei, Lin, Xiong, Wen-Cheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830299/ https://www.ncbi.nlm.nih.gov/pubmed/26679195 http://dx.doi.org/10.1093/cercor/bhv292 |
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