Human Sulfatase-1 Improves the Effectiveness of Cytosine Deaminase Suicide Gene Therapy with 5-Fluorocytosine Treatment on Hepatocellular Carcinoma Cell Line HepG2 In Vitro and In Vivo

BACKGROUND: Human sulfatase-1 (Hsulf-1) is an endosulfatase that selectively removes sulfate groups from heparan sulfate proteoglycans (HSPGs), altering the binding of several growth factors and cytokines to HSPG to regulate cell proliferation, cell motility, and apoptosis. We investigated the role...

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Detalles Bibliográficos
Autores principales: Yang, Xiao-Ping, Liu, Ling, Wang, Ping, Ma, Sheng-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830321/
https://www.ncbi.nlm.nih.gov/pubmed/25963362
http://dx.doi.org/10.4103/0366-6999.156800

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830321/
https://www.ncbi.nlm.nih.gov/pubmed/25963362
http://dx.doi.org/10.4103/0366-6999.156800

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