Induction of serine racemase expression and D-serine release from microglia by amyloid β-peptide

BACKGROUND: Roles for excitotoxicity and inflammation in Alzheimer's disease have been hypothesized. Proinflammatory stimuli, including amyloid β-peptide (Aβ), elicit a release of glutamate from microglia. We tested the possibility that a coagonist at the NMDA class of glutamate receptors, D-se...

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Detalles Bibliográficos
Autores principales: Wu, Sheng-Zhou, Bodles, Angela M, Porter, Mandy M, Griffin, W Sue T, Basile, Anthony S, Barger, Steven W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC483052/
https://www.ncbi.nlm.nih.gov/pubmed/15285800
http://dx.doi.org/10.1186/1742-2094-1-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC483052/
https://www.ncbi.nlm.nih.gov/pubmed/15285800
http://dx.doi.org/10.1186/1742-2094-1-2

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