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IL-12p40/IL-10 Producing preCD8α/Clec9A(+) Dendritic Cells Are Induced in Neonates upon Listeria monocytogenes Infection

Infection by Listeria monocytogenes (Lm) causes serious sepsis and meningitis leading to mortality in neonates. This work explored the ability of CD11c(high) lineage DCs to induce CD8(+) T-cell immune protection against Lm in mice before 7 days of life, a period symbolized by the absence of murine I...

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Detalles Bibliográficos
Autores principales: Torres, David, Köhler, Arnaud, Delbauve, Sandrine, Caminschi, Irina, Lahoud, Mireille H., Shortman, Ken, Flamand, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830566/
https://www.ncbi.nlm.nih.gov/pubmed/27074026
http://dx.doi.org/10.1371/journal.ppat.1005561