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Role of Double-Strand Break End-Tethering during Gene Conversion in Saccharomyces cerevisiae
Correct repair of DNA double-strand breaks (DSBs) is critical for maintaining genome stability. Whereas gene conversion (GC)-mediated repair is mostly error-free, repair by break-induced replication (BIR) is associated with non-reciprocal translocations and loss of heterozygosity. We have previously...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830573/ https://www.ncbi.nlm.nih.gov/pubmed/27074148 http://dx.doi.org/10.1371/journal.pgen.1005976 |