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Selective COX-2 inhibition prevents progressive dopamine neuron degeneration in a rat model of Parkinson's disease

Several lines of evidence point to a significant role of neuroinflammation in Parkinson's disease (PD) and other neurodegenerative disorders. In the present study we examined the protective effect of celecoxib, a selective inhibitor of the inducible form of cyclooxygenase (COX-2), on dopamine (...

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Detalles Bibliográficos
Autores principales: Sánchez-Pernaute, Rosario, Ferree, Andrew, Cooper, Oliver, Yu, Meixiang, Brownell, Anna-Liisa, Isacson, Ole
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC483059/
https://www.ncbi.nlm.nih.gov/pubmed/15285796
http://dx.doi.org/10.1186/1742-2094-1-6