Cargando…

Selective COX-2 inhibition prevents progressive dopamine neuron degeneration in a rat model of Parkinson's disease

Several lines of evidence point to a significant role of neuroinflammation in Parkinson's disease (PD) and other neurodegenerative disorders. In the present study we examined the protective effect of celecoxib, a selective inhibitor of the inducible form of cyclooxygenase (COX-2), on dopamine (...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sánchez-Pernaute, Rosario, Ferree, Andrew, Cooper, Oliver, Yu, Meixiang, Brownell, Anna-Liisa, Isacson, Ole
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2004
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC483059/ https://www.ncbi.nlm.nih.gov/pubmed/15285796 http://dx.doi.org/10.1186/1742-2094-1-6

Ejemplares similares

Neuroinflammation mediated by IL-1β increases susceptibility of dopamine neurons to degeneration in an animal model of Parkinson's disease
por: Koprich, James B, et al.
Publicado: (2008)

Cellular Programming and Reprogramming: Sculpting Cell Fate for the Production of Dopamine Neurons for Cell Therapy
por: Aguila, Julio C., et al.
Publicado: (2012)

New Progress on the Role of Glia in Iron Metabolism and Iron-Induced Degeneration of Dopamine Neurons in Parkinson’s Disease
por: Xu, Huamin, et al.
Publicado: (2018)

Dilated Perivascular Space in the Midbrain May Reflect Dopamine Neuronal Degeneration in Parkinson’s Disease
por: Li, Yanxuan, et al.
Publicado: (2020)

O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease
por: Lee, Byeong Eun, et al.
Publicado: (2020)

The degeneration and replacement of dopamine cells in Parkinson’s disease: the role of aging
por: Rodriguez, Manuel, et al.
Publicado: (2014)

Single-cell genomic profiling of human dopamine neurons identifies a population that selectively degenerates in Parkinson’s disease
por: Kamath, Tushar, et al.
Publicado: (2022)

The Therapeutic Implications of Tea Polyphenols against Dopamine (DA) Neuron Degeneration in Parkinson’s Disease (PD)
por: Zhou, Zhi Dong, et al.
Publicado: (2019)

Metformin Prevents Nigrostriatal Dopamine Degeneration Independent of AMPK Activation in Dopamine Neurons
por: Bayliss, Jacqueline A., et al.
Publicado: (2016)

Capsaicin prevents degeneration of dopamine neurons by inhibiting glial activation and oxidative stress in the MPTP model of Parkinson's disease
por: Chung, Young C, et al.
Publicado: (2017)

Ellagic Acid Prevents Dopamine Neuron Degeneration from Oxidative Stress and Neuroinflammation in MPTP Model of Parkinson’s Disease
por: Ardah, Mustafa T., et al.
Publicado: (2020)

Norfluoxetine Prevents Degeneration of Dopamine Neurons by Inhibiting Microglia-Derived Oxidative Stress in an MPTP Mouse Model of Parkinson's Disease
por: Kim, Kyung In, et al.
Publicado: (2018)

Cerebral dopamine neurotrophic factor–deficiency leads to degeneration of enteric neurons and altered brain dopamine neuronal function in mice
por: Lindahl, Maria, et al.
Publicado: (2019)

Eleven Crucial Pesticides Appear to Regulate Key Genes That Link MPTP Mechanism to Cause Parkinson’s Disease through the Selective Degeneration of Dopamine Neurons
por: Anirudhan, Athira, et al.
Publicado: (2023)

Rhes Counteracts Dopamine Neuron Degeneration and Neuroinflammation Depending on Gender and Age
por: Costa, Giulia, et al.
Publicado: (2018)

Dopamine Transporter Imaging for Frontotemporal Lobar Degeneration With Motor Neuron Disease
por: Kobayashi, Ryota, et al.
Publicado: (2022)

Progressive aggregation of alpha-synuclein and selective degeneration of Lewy inclusion-bearing neurons in a mouse model of parkinsonism
por: Osterberg, Valerie R., et al.
Publicado: (2015)

Progressive decline of glucocerebrosidase in aging and Parkinson's disease
por: Rocha, Emily M, et al.
Publicado: (2015)

Replacing Dopamine Neurons in Parkinson’s Disease: How did it happen?
por: Björklund, Anders, et al.
Publicado: (2017)

Dopamine Neuron Challenge Test for early detection of Parkinson’s disease
por: Zhou, Jingheng, et al.
Publicado: (2021)

Genetic elimination of dopamine vesicular stocks in the nigrostriatal pathway replicates Parkinson’s disease motor symptoms without neuronal degeneration in adult mice
por: Isingrini, Elsa, et al.
Publicado: (2017)

Sexual dysfunction precedes motor defects, dopaminergic neuronal degeneration, and impaired dopamine metabolism: Insights from Drosophila model of Parkinson’s disease
por: Koza, Zevelou, et al.
Publicado: (2023)

Oct4-Induced Reprogramming Is Required for Adult Brain Neural Stem Cell Differentiation into Midbrain Dopaminergic Neurons
por: Deleidi, Michela, et al.
Publicado: (2011)

Dopamine transporter neuroimaging accurately assesses the maturation of dopamine neurons in a preclinical model of Parkinson’s disease
por: Goggi, Julian L., et al.
Publicado: (2020)

Edaravone Guards Dopamine Neurons in a Rotenone Model for Parkinson's Disease
por: Xiong, Nian, et al.
Publicado: (2011)

Calcium, Dopamine and Neuronal Calcium Sensor 1: Their Contribution to Parkinson’s Disease
por: Catoni, Cristina, et al.
Publicado: (2019)

LRRK2 Expression Is Deregulated in Fibroblasts and Neurons from Parkinson Patients with Mutations in PINK1
por: Azkona, Garikoitz, et al.
Publicado: (2016)

Activation of the mitochondrial unfolded protein response promotes longevity and dopamine neuron survival in Parkinson’s disease models
por: Cooper, Jason F., et al.
Publicado: (2017)

Sox-2 Positive Neural Progenitors in the Primate Striatum Undergo Dynamic Changes after Dopamine Denervation
por: Ordoñez, Cristina, et al.
Publicado: (2013)

Orchestrated increase of dopamine and PARK mRNAs but not miR-133b in dopamine neurons in Parkinson's disease()
por: Schlaudraff, Falk, et al.
Publicado: (2014)

The foxa2 Gene Controls the Birth and Spontaneous Degeneration of Dopamine Neurons in Old Age
por: Kittappa, Raja, et al.
Publicado: (2007)

Alpha-Synuclein Disrupted Dopamine Homeostasis Leads to Dopaminergic Neuron Degeneration in Caenorhabditis elegans
por: Cao, Pengxiu, et al.
Publicado: (2010)

Interleukin-4 Contributes to Degeneration of Dopamine Neurons in the Lipopolysaccharide-treated Substantia Nigra in vivo
por: Bok, Eugene, et al.
Publicado: (2018)

Intermittent Fasting Applied in Combination with Rotenone Treatment Exacerbates Dopamine Neurons Degeneration in Mice
por: Tatulli, Giuseppe, et al.
Publicado: (2018)

Correction: Sox-2 Positive Neural Progenitors in the Primate Striatum Undergo Dynamic Changes after Dopamine Denervation
por: Ordoñez, Cristina, et al.
Publicado: (2013)

Degeneration of Dopaminergic Neurons Due to Metabolic Alterations and Parkinson’s Disease
por: Song, Juhyun, et al.
Publicado: (2016)

Neuron loss and degeneration in the progression of TDP-43 in frontotemporal lobar degeneration
por: Yousef, Ahmed, et al.
Publicado: (2017)

COX-2 in the neurodegenerative process of Parkinson's disease
por: Teismann, Peter
Publicado: (2012)

Evidence for Gender-Specific Transcriptional Profiles of Nigral Dopamine Neurons in Parkinson Disease
por: Simunovic, Filip, et al.
Publicado: (2010)

Asymmetric Presynaptic Depletion of Dopamine Neurons in a Drosophila Model of Parkinson’s Disease
por: Zhang, Jiajun, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_t5du4insvm4lh546ro88ja8mto