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High-Dimensional Analysis of Acute Myeloid Leukemia Reveals Phenotypic Changes in Persistent Cells during Induction Therapy

The plasticity of AML drives poor clinical outcomes and confounds its longitudinal detection. However, the immediate impact of treatment on the leukemic and non-leukemic cells of the bone marrow and blood remains relatively understudied. Here, we conducted a pilot study of high dimensional longitudi...

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Detalles Bibliográficos
Autores principales: Ferrell, Paul Brent, Diggins, Kirsten Elizabeth, Polikowsky, Hannah Grace, Mohan, Sanjay Ram, Seegmiller, Adam C., Irish, Jonathan Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830605/
https://www.ncbi.nlm.nih.gov/pubmed/27074138
http://dx.doi.org/10.1371/journal.pone.0153207