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High-Dimensional Analysis of Acute Myeloid Leukemia Reveals Phenotypic Changes in Persistent Cells during Induction Therapy
The plasticity of AML drives poor clinical outcomes and confounds its longitudinal detection. However, the immediate impact of treatment on the leukemic and non-leukemic cells of the bone marrow and blood remains relatively understudied. Here, we conducted a pilot study of high dimensional longitudi...
Autores principales: | Ferrell, Paul Brent, Diggins, Kirsten Elizabeth, Polikowsky, Hannah Grace, Mohan, Sanjay Ram, Seegmiller, Adam C., Irish, Jonathan Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830605/ https://www.ncbi.nlm.nih.gov/pubmed/27074138 http://dx.doi.org/10.1371/journal.pone.0153207 |
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