Development and Validation of Stability-Indicating Method for Estimation of Chlorthalidone in Bulk and Tablets with the Use of Experimental Design in Forced Degradation Experiments

Chlorthalidone was subjected to various forced degradation conditions. Substantial degradation of chlorthalidone was obtained in acid, alkali, and oxidative conditions. Further full factorial experimental design was applied for acid and alkali forced degradation conditions, in which strength of acid...

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Detalles Bibliográficos
Autores principales: Sonawane, Sandeep, Jadhav, Sneha, Rahade, Priya, Chhajed, Santosh, Kshirsagar, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830733/
https://www.ncbi.nlm.nih.gov/pubmed/27123364
http://dx.doi.org/10.1155/2016/4286482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830733/
https://www.ncbi.nlm.nih.gov/pubmed/27123364
http://dx.doi.org/10.1155/2016/4286482

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