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Chronic Myeloid Leukemia and Hepatoblastoma: Two Cancer Models to Link Metabolism to Stem Cells

Low oxygen tension is a critical aspect of the stem cell niche where stem cells are long-term maintained. In “physiologically hypoxic” stem cell niches, low oxygen tension restrains the clonal expansion of stem cells without blocking their cycling, thereby contributing substantially to favor their s...

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Detalles Bibliográficos
Autores principales: Cipolleschi, Maria Grazia, Marzi, Ilaria, Rovida, Elisabetta, Dello Sbarba, Persio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830810/
https://www.ncbi.nlm.nih.gov/pubmed/27148487
http://dx.doi.org/10.3389/fonc.2016.00095