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Failure of the Nemo Trial: Bumetanide Is a Promising Agent to Treat Many Brain Disorders but Not Newborn Seizures

The diuretic bumetanide failed to treat acute seizures due to hypoxic ischemic encephalopathy (HIE) in newborn babies and was associated with hearing loss (NEMO trial, Pressler et al., 2015). On the other hand, clinical and experimental observations suggest that the diuretic might provide novel ther...

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Detalles Bibliográficos
Autores principales: Ben-Ari, Yehezkel, Damier, Philippe, Lemonnier, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830840/
https://www.ncbi.nlm.nih.gov/pubmed/27147965
http://dx.doi.org/10.3389/fncel.2016.00090