Extended evaluation on the ES-D3 cell differentiation assay combined with the BeWo transport model, to predict relative developmental toxicity of triazole compounds

The mouse embryonic stem D3 (ES-D3) cell differentiation assay is based on the morphometric measurement of cardiomyocyte differentiation and is a promising tool to detect developmental toxicity of compounds. The BeWo transport model, consisting of BeWo b30 cells grown on transwell inserts and mimick...

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Detalles Bibliográficos
Autores principales: Li, Hequn, Flick, Burkhard, Rietjens, Ivonne M. C. M., Louisse, Jochem, Schneider, Steffen, van Ravenzwaay, Bennard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Reproductive Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830886/
https://www.ncbi.nlm.nih.gov/pubmed/26047666
http://dx.doi.org/10.1007/s00204-015-1541-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830886/
https://www.ncbi.nlm.nih.gov/pubmed/26047666
http://dx.doi.org/10.1007/s00204-015-1541-6

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