CryoEM structures of two spliceosomal complexes: starter and dessert at the spliceosome feast

The spliceosome is formed on pre-mRNA substrates from five small nuclear ribonucleoprotein particles (U1, U2, U4/U6 and U5 snRNPs), and numerous non-snRNP factors. Saccharomyces cerevisiae U4/U6.U5 tri-snRNP comprises U5 snRNA, U4/U6 snRNA duplex and approximately 30 proteins and represents a substa...

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Detalles Bibliográficos
Autores principales: Nguyen, Thi Hoang Duong, Galej, Wojciech P, Fica, Sebastian M, Lin, Pei-Chun, Newman, Andrew J, Nagai, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830896/
https://www.ncbi.nlm.nih.gov/pubmed/26803803
http://dx.doi.org/10.1016/j.sbi.2015.12.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830896/
https://www.ncbi.nlm.nih.gov/pubmed/26803803
http://dx.doi.org/10.1016/j.sbi.2015.12.005

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