PML is required for telomere stability in non-neoplastic human cells

Telomeres interact with numerous proteins, including components of the shelterin complex, whose alteration, similarly to proliferation-induced telomere shortening, initiates cellular senescence. In tumors, telomere length is maintained by Telomerase activity or by the Alternative Lengthening of Telo...

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Detalles Bibliográficos
Autores principales: Marchesini, M, Matocci, R, Tasselli, L, Cambiaghi, V, Orleth, A, Furia, L, Marinelli, C, Lombardi, S, Sammarelli, G, Aversa, F, Minucci, S, Faretta, M, Pelicci, P G, Grignani, F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830905/
https://www.ncbi.nlm.nih.gov/pubmed/26119943
http://dx.doi.org/10.1038/onc.2015.246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830905/
https://www.ncbi.nlm.nih.gov/pubmed/26119943
http://dx.doi.org/10.1038/onc.2015.246

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