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The dynamic behavior of Ect2 in response to DNA damage

Ect2 is a BRCT-containing guanidine exchange factor for Rho GTPases. It is essential for cytokinesis and is also involved in tumorigenesis. Since most BRCT-containing proteins are involved in DNA damage response and/or DNA repair, we tested whether Ect2 plays similar roles. We report that in primary...

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Detalles Bibliográficos
Autores principales: He, Dan, Xiang, Jinnan, Li, Baojie, Liu, Huijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830932/
https://www.ncbi.nlm.nih.gov/pubmed/27074761
http://dx.doi.org/10.1038/srep24504