Plasmacytoid dendritic cells orchestrate TLR7-mediated innate and adaptive immunity for the initiation of autoimmune inflammation

Endosomal toll-like receptor (TLR)-mediated detection of viral nucleic acids (NAs) and production of type I interferon (IFN-I) are key elements of antiviral defense, while inappropriate recognition of self NAs with the induction of IFN-I responses is linked to autoimmunity such as psoriasis and syst...

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Detalles Bibliográficos
Autores principales: Takagi, Hideaki, Arimura, Keiichi, Uto, Tomofumi, Fukaya, Tomohiro, Nakamura, Takeshi, Choijookhuu, Narantsog, Hishikawa, Yoshitaka, Sato, Katsuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830934/
https://www.ncbi.nlm.nih.gov/pubmed/27075414
http://dx.doi.org/10.1038/srep24477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830934/
https://www.ncbi.nlm.nih.gov/pubmed/27075414
http://dx.doi.org/10.1038/srep24477

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