Structural insights and functional implications of inter-individual variability in β(2)-adrenergic receptor

The human β(2)-adrenergic receptor (β(2)AR) belongs to the G protein-coupled receptor (GPCR) family and due to its central role in bronchodilation, is an important drug target. The inter-individual variability in β(2)AR has been implicated in disease susceptibility and differential drug response. In...

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Detalles Bibliográficos
Autores principales: Tandale, Aditi, Joshi, Manali, Sengupta, Durba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830965/
https://www.ncbi.nlm.nih.gov/pubmed/27075228
http://dx.doi.org/10.1038/srep24379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830965/
https://www.ncbi.nlm.nih.gov/pubmed/27075228
http://dx.doi.org/10.1038/srep24379

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