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Association between PPAR-γ2 Pro12Ala genotype and insulin resistance is modified by circulating lipids in Mexican children

The Pro12Ala (rs1801282) polymorphism in peroxisome proliferator-activated receptor-γ2 (PPAR-γ2) has been convincingly associated with insulin resistance (IR) and type 2 diabetes (T2D) among Europeans, in interaction with a high-fat diet. Mexico is disproportionally affected by obesity and T2D howev...

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Detalles Bibliográficos
Autores principales: Stryjecki, Carolina, Peralta-Romero, Jesus, Alyass, Akram, Karam-Araujo, Roberto, Suarez, Fernando, Gomez-Zamudio, Jaime, Burguete-Garcia, Ana, Cruz, Miguel, Meyre, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830984/
https://www.ncbi.nlm.nih.gov/pubmed/27075119
http://dx.doi.org/10.1038/srep24472