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DNA context represents transcription regulation of the gene in mouse embryonic stem cells

Understanding gene regulatory information in DNA remains a significant challenge in biomedical research. This study presents a computational approach to infer gene regulatory programs from primary DNA sequences. Using DNA around transcription start sites as attributes, our model predicts gene regula...

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Detalles Bibliográficos
Autores principales: Ha, Misook, Hong, Soondo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831003/
https://www.ncbi.nlm.nih.gov/pubmed/27075878
http://dx.doi.org/10.1038/srep24343