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Role of EP(2) and EP(4) receptors in airway microvascular leak induced by prostaglandin E(2)

BACKGROUND AND PURPOSE: Airway microvascular leak (MVL) involves the extravasation of proteins from post‐capillary venules into surrounding tissue. MVL is a cardinal sign of inflammation and an important feature of airway inflammatory diseases such as asthma. PGE(2), a product of COX‐mediated metabo...

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Detalles Bibliográficos
Autores principales: Jones, Victoria C, Birrell, Mark A, Maher, Sarah A, Griffiths, Mark, Grace, Megan, O'Donnell, Valerie B, Clark, Stephen R, Belvisi, Maria G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831025/
https://www.ncbi.nlm.nih.gov/pubmed/26639895
http://dx.doi.org/10.1111/bph.13400