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Single-cell profiling of lncRNAs in the developing human brain

Single-cell RNA-seq in samples from the human neocortex demonstrate that long noncoding RNAs (lncRNAs) are abundantly expressed in specific individual brain cells, despite being hard to detect in bulk samples. This result suggests that the lncRNAs might have important functions in specific cell type...

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Detalles Bibliográficos
Autores principales: Ma, Qing, Chang, Howard Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831122/
https://www.ncbi.nlm.nih.gov/pubmed/27079200
http://dx.doi.org/10.1186/s13059-016-0933-0