Combination of nanoparticle-based therapeutic vaccination and transient ablation of regulatory T cells enhances anti-viral immunity during chronic retroviral infection

BACKGROUND: Regulatory T cells (Tregs) have been shown to limit anti-viral immunity during chronic retroviral infection and to restrict vaccine-induced T cell responses. The objective of the study was to assess whether a combinational therapy of nanoparticle-based therapeutic vaccination and concomi...

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Detalles Bibliográficos
Autores principales: Knuschke, Torben, Rotan, Olga, Bayer, Wibke, Sokolova, Viktoriya, Hansen, Wiebke, Sparwasser, Tim, Dittmer, Ulf, Epple, Matthias, Buer, Jan, Westendorf, Astrid M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831142/
https://www.ncbi.nlm.nih.gov/pubmed/27076190
http://dx.doi.org/10.1186/s12977-016-0258-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831142/
https://www.ncbi.nlm.nih.gov/pubmed/27076190
http://dx.doi.org/10.1186/s12977-016-0258-9

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