Cargando…

Preclinical exploration of combining plasmacytoid and myeloid dendritic cell vaccination with BRAF inhibition

BACKGROUND: Melanoma is the most lethal type of skin cancer and its incidence is progressively increasing. The introductions of immunotherapy and targeted therapies have tremendously improved the treatment of melanoma. Selective inhibition of BRAF by vemurafenib results in objective clinical respons...

Descripción completa

Detalles Bibliográficos
Autores principales: Tel, Jurjen, Koornstra, Rutger, de Haas, Nienke, van Deutekom, Vincent, Westdorp, Harm, Boudewijns, Steve, van Erp, Nielka, Di Blasio, Stefania, Gerritsen, Winald, Figdor, Carl G., de Vries, I. Jolanda M., Hato, Stanleyson V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831164/
https://www.ncbi.nlm.nih.gov/pubmed/27075584
http://dx.doi.org/10.1186/s12967-016-0844-6