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Preclinical exploration of combining plasmacytoid and myeloid dendritic cell vaccination with BRAF inhibition
BACKGROUND: Melanoma is the most lethal type of skin cancer and its incidence is progressively increasing. The introductions of immunotherapy and targeted therapies have tremendously improved the treatment of melanoma. Selective inhibition of BRAF by vemurafenib results in objective clinical respons...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831164/ https://www.ncbi.nlm.nih.gov/pubmed/27075584 http://dx.doi.org/10.1186/s12967-016-0844-6 |