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Muscle cell identity requires Pax7-mediated lineage-specific DNA demethylation

BACKGROUND: Skeletal muscle stem cells enable the formation, growth, maintenance, and regeneration of skeletal muscle throughout life. The regeneration process is compromised in several pathological conditions, and muscle progenitors derived from pluripotent stem cells have been suggested as a poten...

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Detalles Bibliográficos
Autores principales: Carrió, Elvira, Magli, Alessandro, Muñoz, Mar, Peinado, Miguel A., Perlingeiro, Rita, Suelves, Mònica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831197/
https://www.ncbi.nlm.nih.gov/pubmed/27075038
http://dx.doi.org/10.1186/s12915-016-0250-9