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Inhibition of Gα(s)/cAMP Signaling Decreases TCR-Stimulated IL-2 transcription in CD4(+) T Helper Cells
Background: The role of cAMP in regulating T cell activation and function has been controversial. cAMP is generally known as an immunosuppressant, but it is also required for generating optimal immune responses. As the effect of cAMP is likely to depend on its cellular context, the current study inv...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ubiquity Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831273/ https://www.ncbi.nlm.nih.gov/pubmed/27096000 http://dx.doi.org/10.5334/1750-2187-10-2 |