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Inhibition of Gα(s)/cAMP Signaling Decreases TCR-Stimulated IL-2 transcription in CD4(+) T Helper Cells

Background: The role of cAMP in regulating T cell activation and function has been controversial. cAMP is generally known as an immunosuppressant, but it is also required for generating optimal immune responses. As the effect of cAMP is likely to depend on its cellular context, the current study inv...

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Detalles Bibliográficos
Autores principales:	Hynes, Thomas R., Yost, Evan A., Yost, Stacy M., Hartle, Cassandra M., Ott, Braden J., Berlot, Catherine H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ubiquity Press 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831273/ https://www.ncbi.nlm.nih.gov/pubmed/27096000 http://dx.doi.org/10.5334/1750-2187-10-2

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