N‐acetylcysteine attenuates the development of cardiac fibrosis and remodeling in a mouse model of heart failure

Oxidative stress plays a central role in the pathogenesis of heart failure. We aimed to determine whether the antioxidant N‐acetylcysteine can attenuate cardiac fibrosis and remodeling in a mouse model of heart failure. Minipumps were implanted subcutaneously in wild‐type mice (n = 20) and mice with...

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Detalles Bibliográficos
Autores principales: Giam, Beverly, Chu, Po‐Yin, Kuruppu, Sanjaya, Smith, A. Ian, Horlock, Duncan, Kiriazis, Helen, Du, Xiao‐Jun, Kaye, David M., Rajapakse, Niwanthi W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831326/
https://www.ncbi.nlm.nih.gov/pubmed/27081162
http://dx.doi.org/10.14814/phy2.12757

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831326/
https://www.ncbi.nlm.nih.gov/pubmed/27081162
http://dx.doi.org/10.14814/phy2.12757

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